SEMANA DE LA CIENCIA Y LA TECNOLOGÍA 2020: Inscripción de actividades de divulgación científica hasta el 5 de octubre

En el marco de la celebración de la Semana de la Ciencia y la  Tecnología 2020, el CSIC os invita a organizar actividades de divulgación científica durante todo el mes de noviembre con el objetivo de acercar la tarea científica del CSIC a la sociedad, tal y como se ha hecho en años anteriores.

Se aconseja que la mayoría de las actividades sean online. En el caso de optar por actividades presenciales, éstas deberán organizarse con reserva previa (para poder notificar posibles cambios), en grupos reducidos y siguiendo la normativa que en ese momento nos indiquen las autoridades.

Una vez acordéis la propuesta de actividades de vuestro centro/instituto, como en anteriores ediciones, vuestras actividades han de ser registradas en la intranet del CSIC antes del próximo 5 de octubre. Esto permitirá difundir el alcance, el esfuerzo y las actividades del CSIC de forma conjunta desde páginas web, redes sociales y medios de comunicación.

Web SCT 2020

 

ITQ researchers develop a new theranostic nanomedicine that is more efficient and less aggressive than conventional chemotherapy

[This information is being translated into English]

Un equipo de investigadores del Instituto de Tecnología Química (ITQ), centro mixto de la Universitat Politècnica de València (UPV) y el Consejo Superior de Investigaciones Científicas (CSIC), ha desarrollado una nueva nanomedicina teranóstica para el diagnóstico y tratamiento del cáncer de próstata, basada en el uso de nanopartículas porosas orgánicas COF (covalent organic frameworks), y que destaca por ser más eficiente y menos agresiva que la quimioterapia convencional.

Su funcionamiento se basa en interacciones específicas de tipo antígeno-anticuerpo, que permiten la destrucción selectiva de células cancerosas en la glándula prostática y los ganglios linfáticos locales.

La nueva nanomedicina está compuesta por una nanopartícula de COF en la que se inserta la molécula de un agente terapéutico –en este caso, docetaxel, el fármaco más usado para el tratamiento del cáncer de próstata resistente a la hormonoterapia-; un anticuerpo monoclonal anti-FOLH1, que interacciona selectivamente con receptores de membrana FOLH1 de células de cáncer de próstata; y un agente de imagen, generalmente, un radionúcleo para tomografía de emisión de positrones (PET).

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The ITQ Catalysis for Sustainable Organic Reactions group, in collaboration with other groups, have published in the journal Chemical Science a study on the use of platinum clusters as catalysts for hydrosilylation reactions.

The ITQ Catalysis for Sustainable Organic Reactions group, in collaboration with the Faculty of Chemistry of the Jagiellonian University (Krakow, Poland), the Institute of Molecular Science (ICMol) of the University of Valencia, and the Molecular Recognition and Encapsulation Group (REM) of the Catholic University of Murcia (UCAM), have published in the journal Chemical Science a study on the use of platinum clusters as catalysts for hydrosilylation reactions.

The Pt–catalyzed hydrosilylation reaction is a fundamental transformation in industrial and academic chemistry to finally give silicones, performed in solution without extracting the Pt atoms, thus contaminating with Pt many daily objects. Our work shows that the reaction proceeds not with the original Pt catalyst added but with Pt–Si–H clusters of 3–5 atoms (metal(oid) association) formed in-situ, in part–per–million amounts (ppm). This metal(oid) association enables the design of new solid catalysts, which paves the way for a more environmentally–benign application of this industrial reaction.

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A new publication in J. Phys. Chem. Lett. describes the work by ITQ researchers

It is known that the synthesis of zeolites can become more selective by introducing organic molecules (named Structure Directing Agents, SDA) in the gel. If SDAs match the zeolite micropore, then the short-range energy stabilization (van der Waals) makes the system more stable. From a few decades, the design of new SDAs has led to notable breakthroughs allowing the synthesis of many new and different zeolites. Recently, the combination of computational methods and algorithms for the treatment of big data as well as the advent of artificial intelligence is contributing to taking the state of the art a step forward.

A new publication in J. Phys. Chem. Lett. describes the work by ITQ researchers in this sense. The new algorithm includes the calculation of three structural parameters for each SDA, out of more than 500 chosen from a database. These three parameters can be confronted with other parameters related to micropore size and a shortlist of candidate SDAs for the synthesis of the target zeolite is proposed by the software. ITE has been the zeolite chosen to illustrate and benchmark the power of this approach, which can be readily used for any cage-containing zeolite.  J. Phys. Chem. Lett has published a ‘LiveSlides’ as supporting information of this publication.

 

 

 

 

 

ITQ researchers participate in the European project “FlowPhotoChem”, sunlight to convert water and CO2 into clean chemicals

Researchers from the Institute of Chemical Technology (UPV-CSIC), participate in the European project “FlowPhotoChem” (https://www.flowphotochem.eu/) in the area of ​​Nanotechnology, Advanced Materials, Biotechnology and Advanced Processing and Manufacturing, of the program “Horizon 2020” framework of the European Union (EU).

The European Green Deal sets out to make Europe climate neutral by 2050, and the Clean Planet for All strategy set out ambitious targets to reduce carbon dioxide (CO2) emissions in the EU by 40% by 2030 and by 80-95% by 2050. One of the largest polluters in Europe is the chemical industry, emitting over 145 million tonnes of COequivalents each year.

As part of the “FlowPhotoChem” project, the ITQ group, led by Professor Hermenegildo García, is working on the development of innovative technologies that, using concentrated solar energy and advanced catalysts, will make it possible to convert water and CO2 into valuable chemical products. Postdoctoral researchers with a notable scientific career and training in the area, such as Dr. Josep Albero and Ana Primo, also participate in the ITQ team. “Instead of generating CO2, the integrated ‘FlowPhotoChem’ system will use CO2 as a carbon source to produce chemicals without the use of fossil fuels, reducing Europe’s greenhouse gas emissions and contributing to a cleaner planet”, Hermenegildo García points out. “One of the major innovations of the project is the use of sunlight as an energy source to carry out the transformation of CO2”, comments Dr. Albero.

During the project, research teams from Ireland, Germany, Hungary, Spain, Switzerland, the Netherlands, Uganda and the UK will develop better materials, innovative reactors and advanced computer models to build a proof-of-concept, integrated modular system to convert CO2 into ethylene, a valuable industrial chemical, using concentrated sunlight.

“Environmental sustainability and scalability will be key parts of the design process to secure the system in the future. To ensure that the FlowPhotoChem modular system successfully reaches the market to reduce CO2 emissions, the team will work with chemical companies that could use the technology developed in the project“, concludes Hermenegildo García.

 

European Commission selects platform created by ITQ to design hydrogen generators

Researchers from the Institute of Chemical Technology (UPV-CSIC), has been selected as “Excellent Innovation” by the Innovation Radar of the European Commission.

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ITQ researchers design a new internal combustion gear that does not generate harmful gases

Researchers from the Institute of Chemical Technology (UPV-CSIC) have designed a new internal combustion engine that does not generate gases that are harmful to health or carbon dioxide (CO2), and which also stands out for its high efficiency and complies with emission regulations scheduled for 2040.

Pre-enrollment period opens again to enroll in the master of sustainable chemistry at the UPV in the 2020-21 academic year”

The Master’s Degree in Sustainable Chemistry aims to ensure that students can develop new chemical processes that are efficient, economically viable, and that are carried out in a way that respects the environment. This will minimize the consumption of energy and raw materials and also reduce the risks associated with the production, handling, and use of chemical products necessary for our current life system.

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“Hydrolase–like catalysis and structural resolution of natural products by a metal–organic framework”, una colaboración entre el ITQ, UPV–CSIC, y otros institutos ha sido publicado en “Nature Commun.”

El trabajo”Hydrolase–like catalysis and structural resolution of natural products by a metal–organic framework”, una colaboración entre el Instituto de Tecnología Química (ITQ, UPV–CSIC), el Instituto de Ciencia Molecular (ICMol, UV) y el Dipartimento di Chimica e Tecnologie Chimiche (CTC) de la Università Della Calabria, ha sido publicado en la revista Nature Communications.

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