«XeNMR technique: from microporous solids till biology and medical imaging»

(ATENCIÓN: CAMBIO DE HORA)
El próximo día 3 de febrero a las 10:30 horas (en lugar de las 12:00h, como se anunció inicialmente) en el salón de Actos del ITQ tendrá lugar la charla titulada «XeNMR technique: from microporous solids till biology and medical imaging«, impartida por el Profesor Jacques Fraissard, de la Université Pierre et Marie Curie, Paris VI (Francia).
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A “pot-pourri” of 129 Xe NMR technique
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The 129Xe NMR technique introduced in 1980 allows the determination of pore size, location and charge of compensating cations, structural defects, distribution of adsorbed species, etc. It is applied for the characterization of a lot of solids: zeolites, mesoporous silica, clays, liquid crystals, metal-organic framework compounds (mainly their elasticity), carbons, polymers, diffusion in porous structures and even in archaeology.
Since 2000, this technique has taken a new turn with the advent of laser-hyperpolarized xenon (HP-Xe) in the characterization of materials and organisms. The use of HP-Xe increases the sensitivity for the detection of xenon by several orders of magnitude. The range of its applications becomes wider each day. Now this monotonic probe allows for remarkable explorations ranging from intricate experiments on single-crystal surfaces to the study of the complex nature of gas exchange in mammalian lungs. For example, encaged in a cryptophane cage bearing a ligand, xenon is a very sensitive sensor for detecting biomedically relevant protein targets or metal cations involved in many pathological and physiological processes. Medical applications increase each day, such as: xenon dissolved in the blood for the measurement of the rate of blood in arteries and veins, xenon imaging in brain or human lungs collected in vivo.
We will give some applications of this universal probe for material and biological characterizations.